Prion protein gene frequencies in three Sicilian dairy sheep populations
نویسندگان
چکیده
منابع مشابه
Polymorphism of Prion Protein Gene (PRNP) in Iranian Holstein and Two Local Cattle Populations (Golpayegani and Sistani) of Iran
Bovine spongiform encephalopathy (BSE) is a fatal infectious neurodegenerative disease in cattle, characterized by the accumulation of an abnormal, proteaseresistant prion protein (PrPSc) in the brain. BSE is similar to scrapie in sheep and goats and Creuzfeldt-Jakob disease in humans. Susceptibility in cattle hasbeen shown to be under the influence of two polymorphic locations, which are...
متن کاملPrion protein gene (PrP) polymorphisms in healthy sheep in Turkey.
Scrapie, a transmissible spongiform encephalopathy (TSE) or prion disease, is a fatal, neurodegenerative disease in sheep and goats. This disease has been known in Europe for more than 250 years. Susceptibility to scrapie is associated with polymorphisms in the sheep prion protein gene (PrP) gene. In sheep, polymorphism in the PrP gene has been identified at a number of codons, and polymorphism...
متن کاملMolecular evolution of the sheep prion protein gene.
Transmissible spongiform encephalopathies (TSEs) are infectious, fatal neurodegenerative diseases characterized by aggregates of modified forms of the prion protein (PrP) in the central nervous system. Well known examples include variant Creutzfeldt-Jakob Disease (vCJD) in humans, BSE in cattle, chronic wasting disease in deer and scrapie in sheep and goats. In humans, sheep and deer, disease s...
متن کاملMetabolic gene polymorphism frequencies in control populations.
Using the International Project on Genetic Susceptibility to Environmental Carcinogens (GSEC) database containing information on over 15,000 control (noncancer) subjects, the allele and genotype frequencies for many of the more commonly studied metabolic genes (CYP1A1, CYP2E1, CYP2D6, GSTM1, GSTT1, NAT2, GSTP, and EPHX) in the human population were determined. Major and significant differences ...
متن کاملThe Distribution of Gene Frequencies in Populations.
The effects of the various evolutionary factors-mutation, cross breeding,. selection and inbreeding-can be reduced to common terms by considering the rates of change which they tend to bring about in the relative frequencies of alleles.' In the absence of such factors, there is constancy of gene frequencies from the symmetry of the Mendelian mechanism. The frequency (q) of a given gene changes ...
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ژورنال
عنوان ژورنال: Italian Journal of Animal Science
سال: 2008
ISSN: 1828-051X
DOI: 10.4081/ijas.2008.87